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A kill switch for epilepsy? China cuts seizures by 92.6% in first human chemogenetic trial

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SCMP - Feed 91
By Shi Huang
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A kill switch for epilepsy? China cuts seizures by 92.6% in first human chemogenetic trial
Photo / Coverage: SCMP - Feed 91Credit: Shi Huang
EXECUTIVE SUMMARY

For people living with refractory epilepsy, the brain is like a city that can suffer a blackout any time lightning strikes. Without warning, an abnormal neural discharge can sweep through the intracranial circuits, leaving behind convulsions, loss of consciousness and years of lingering panic. Around one-third of epilepsy patients worldwide are completely unresponsive to existing medications, while traditional craniotomy resection surgery often carries the risk of irreversible neurological...

Key Takeaways

  • A kill switch for epilepsy?
  • China cuts seizures by 92.6% in first human chemogenetic trial.
  • For people living with refractory epilepsy, the brain is like a city that can suffer a blackout any time lightning strikes.

For people living with refractory epilepsy, the brain is like a city that can suffer a blackout any time lightning strikes. Without warning, an abnormal neural discharge can sweep through the intracranial circuits, leaving behind convulsions, loss of consciousness and years of lingering panic. Around one-third of epilepsy patients worldwide are completely unresponsive to existing medications, while traditional craniotomy resection surgery often carries the risk of irreversible neurological...

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